Reproductive Hazards


Standard Operating Procedures (SOPs) are intended to provide you with general guidance on how to safely work with a specific class of chemical or hazard.  This SOP is generic in nature.  It addresses the use and handling of substances by hazard class only.  In some instances multiple SOPs may be applicable for a specific chemical (i.e. both the SOPs for flammable liquids and carcinogens would apply to benzene).  If you have any questions concerning the applicability of any items listed in this procedure, contact EH&S 1-2356 or the Principal Investigator.


Reproductive hazards are substances which affect the reproductive capabilities including chromosomal damage (mutagens) and effects on the fetus (teratogens).




Personnel:         Wash hands and arms with soap and water following any skin contact with reproductive hazards.


Area:                Carefully clean work area after use.


Equipment:        Decontaminate vacuum pumps or other contaminated equipment (glassware) before removing them from the area.



Protection:      Eye protection in the form of safety glasses must be worn at all times when handling reproductive hazards.  Ordinary (prescription) glasses do not provide adequate protection. Adequate safety glasses must meet rigorous tests and safety standards according to ANSI Z.87.1 and must be equipped with side shields.  Safety glasses with side shields do not provide protection from splashes, therefore, when the potential for splash hazard exists, other eye protection or face protection must be worn.


Eyewash:         Where the eyes or body of any person may be exposed to reproductive hazards, suitable facilities for quick drenching or flushing of the eyes and body shall be provided within the work area for immediate emergency use.  Bottle type eyewash stations are not acceptable.


Fume hood:     Manipulation of reproductive hazards should be carried out in a fume hood.


Gloves:           Gloves should be worn when handling reproductive hazards.  Disposable latex or nitrile gloves provide adequate protection against accidental hand contact with small quantities of most laboratory chemicals.  Lab workers should contact EH&S 2338 for advice on chemical resistant glove selection when direct or prolonged contact with hazardous chemicals is anticipated.



Assessment:   Hazard assessment should focus on proper handling techniques, education of laboratory workers concerning the health risks posed by reproductive hazards.





Apparel:          Lab coats, closed toed shoes and long sleeved clothing should be worn when handling reproductive hazards.  Additional protective clothing should be worn if the possibility of skin contact is likely.


Shielding:        Safety shielding is required any time there is a risk of explosion, splash hazard or a highly exothermic reaction.  All manipulations of reproductive hazards that pose this risk should occur in a fume hood with the sash in the lowest feasible position.  Portable shields, which provide protection to all laboratory occupants, are acceptable.



Shower:           A safety or drench shower should be immediately accessible at all times when working with reproductive hazards.


Labels:            Containers: All reproductive hazards must be clearly labeled with the correct chemical name.  Handwritten labels are acceptable; chemical formulas and structural formulas are not acceptable.


Spills:              Please See Spill Cleanup Procedures



Protection:      Evacuated glassware can implode and eject flying glass, and chemicals.  Vacuum work involving reproductive hazards must be conducted in a fume hood.


                        Mechanical vacuum pumps must be protected using cold traps and where appropriate, filtered to prevent particulate release.  The exhaust for the pumps must be vented into an exhaust hood.




All waste shall be placed in closed containers, properly labeled and moved to the Hazardous Waste Accumulation Structure (south west corner of SGM).  Notify Roger Clark of Waste to be picked up from the Hazardous Waste Accumulation area.